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Most benzoquinones reacted relatively quickly where 450 had a rate constant of 1.50 × 10 3 s −1 compared to 2-methylbenzoquinone ( 451 ), 2- tert -butylbenzoquinone ( 452 ), and 2,5-dimethylbenzoquinone ( 453 ) having pseudo-first order rate constants of 3.2 × 10 2 , 2.3 × 10 1 , and 7.3 × 10 −1 s −1 , respectively (entries 1-4, Table 9)
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Key genes involved in mitochondrial biogenesis, such as peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) and mitochondrial transcription factor A (TFAM), witness an uptick in their expression due to NRF2 activation [151]